The Critical Role of Recirculating Chillers in Biopharmaceutical Manufacturing
Introduction
Modern biotechnology hinges on the precise operation and performance of bioreactors, sophisticated vessels where cells are cultivated to produce life-altering vaccines, critical enzymes, and revolutionary protein-based therapeutics, including insulin and monoclonal antibodies (mAbs). Within these controlled ecosystems, every parameter – temperature, pH levels, nutrient concentrations, and gas flow rates – must be meticulously calibrated to achieve optimal cell growth, productivity, and product quality.